Regulation of ergotoxine biosynthesis in Claviceps purpurea submerged fermentation |
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| Authors: | A Puc S Miličić M Kremser H Sočič |
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| Institution: | (1) LEK, Pharmaceutical and Chemical Works, YU-61000 Ljubljana, Yugoslavia;(2)  Boris Kidri  Institute of Chemistry, Hajdrihova 19, YU-61115 Ljubljana, Yugoslavia |
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| Abstract: | Summary The effect of exogenously administered l-valine on the ratio of ergocornine/ergokryptine in submerged cultures of Claviceps purpurea was studied. The desired ratio of alkaloids (1:1) was achieved by the use of very small concentrations of l-valine when proper conditions had been established. |
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