Chromosome condensation: packaging the genome |
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Authors: | Uhlmann F |
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Institution: | Chromosome Segregation Laboratory, Imperial Cancer Research Fund, 44 Lincoln's Inn Fields, WC2A 3PX, London, UK. f.uhlmann@icrf.icnet.uk |
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Abstract: | The packaging of centimetre long DNA molecules into compact metaphase chromosomes is essential for genome segregation in anaphase. The chromosomal condensin complex plays a crucial part in this packaging, and important new insight into condensin action in vitro and in vivo has recently been gained. |
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