Comparison of Hypoglycemic Activity of Fermented Mushroom of Inonotus obliquus Rich in Vanadium and Wild-Growing I. obliquus |
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Authors: | Yibing Zhang Yong Zhao Haifeng Cui Chunyu Cao Jianyou Guo Sha Liu |
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Affiliation: | School of Traditional Chinese Medicine, Chongqing Medical University, Jieqing Road, Huxi University City, Chongqing, 401331, People's Republic of China. |
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Abstract: | The effects of vanadium-enriched and wild Inonotus obliquus were tested on hyperglycemic mice. The vanadium content of the culture medium was 0.6%, reaching a concentration of 3.0?mg/g in the cultured mushroom while in the wild variety is 1/100 of that amount. The toxicity of vanadium at the 3.0?mg/g level is negligible, but its anti-diabetic effects are significantly different to those of the wild variety (p?0.05). Due to its high bioavailability and low toxicity, vanadium-enriched I. obliquus could be used as a means of vanadium supplementation, with expectation of obtaining higher bioavailability and lower toxicity in animals. |
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