Physiological Levels of Glucose Induce Membrane Vesicle Secretion and Affect the Lipid and Protein Composition of Yersinia pestis Cell Surfaces |
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| Authors: | Anna M. Kolodziejek Allan B. Caplan Gregory A. Bohach Andrzej J. Paszczynski Scott A. Minnich Carolyn J. Hovde |
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| Affiliation: | School of Food Science, University of Idaho, Moscow, Idaho, USAa;Department of Microbiology, Molecular Biology, and Biochemistry, University of Idaho, Moscow, Idaho, USAb |
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| Abstract: | Yersinia pestis grown with physiologic glucose increased cell autoaggregation and deposition of extracellular material, including membrane vesicles. Membranes were characterized, and glucose had significant effects on protein, lipid, and carbohydrate profiles. These effects were independent of temperature and the biofilm-related locus pgm and were not observed in Yersinia pseudotuberculosis. |
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