| 肠道微生物与骨质疏松相关性的研究进展 |
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| 引用本文： | 魏晋鹏,常峰.肠道微生物与骨质疏松相关性的研究进展[J].微生物学通报,2023,50(2):729-741. |
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| 作者姓名： | 魏晋鹏 常峰 |
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| 作者单位： | 山西医科大学第五临床医学院, 山西 太原 030012;山西省人民医院骨科, 山西 太原 030012 |
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| 基金项目： | 山西省卫生健康委科研计划(2018029,2019019) |
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| 摘 要： | 随着人口老龄化问题的加剧，骨质疏松症的高发生率降低了人们的生活质量。越来越多的证据表明，肠道微生物群与骨代谢联系密切，肠道微生物群稳态的破坏会导致宿主的病理生理反应，从而引起骨质疏松。通过研究两者之间的相互作用，或许能为骨质疏松症的预防及相关诊疗提供有价值的帮助。本文就目前肠道微生物与骨质疏松症相关机制和主要治疗的研究现状作一综述。
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| 关 键 词： | 骨质疏松症 肠道菌群 骨免疫学 骨微生物学 治疗 |
| 收稿时间： | 2022/5/22 0:00:00 |
Advances in the relationship between gut microbiota and osteoporosis |
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| WEI Jinpeng,CHANG Feng.Advances in the relationship between gut microbiota and osteoporosis[J].Microbiology,2023,50(2):729-741. |
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| Authors: | WEI Jinpeng CHANG Feng |
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| Institution: | The Fifth Clinical Medical College of Shanxi Medical University, Taiyuan 030012, Shanxi, China; Department of Orthopedics, Shanxi Provincial People''s Hospital, Taiyuan 030012, Shanxi, China |
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| Abstract: | The high incidence of osteoporosis in the aging population reduces the quality of life. There is growing evidence that the gut microbiota is closely linked to bone metabolism. Gut microbiota disorder will lead to pathophysiological responses in the host, which can cause osteoporosis. The research on the interactions between gut microbiota and osteoporosis may contribute to the management of osteoporosis-related conditions. This paper reviews the advances in the interactions between gut microbiota and osteoporosis and the relevant therapies. |
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| Keywords: | osteoporosis gut microbiota Osteoimmunology Osteomicrobiology treatment |
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