Modeling and analysis of soybean (Glycine max. L) Cu/Zn,Mn and Fe superoxide dismutases |
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| Authors: | V. Ramana Gopavajhula K. Viswanatha Chaitanya P. Akbar Ali Khan Jilani P. Shaik P. Narasimha Reddy Mohammad Alanazi |
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| Affiliation: | 1.Department of Biotechnology, GITAM University, Visakhapatnam, India.;2.Genome Research Chair, Department of Biochemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia. |
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| Abstract: | Superoxide dismutase (SOD, EC 1.15.1.1) is an important metal-containing antioxidant enzyme that provides the first line of defense against toxic superoxide radicals by catalyzing their dismutation to oxygen and hydrogen peroxide. SOD is classified into four metalloprotein isoforms, namely, Cu/Zn SOD, Mn SOD, Ni SOD and Fe SOD. The structural models of soybean SOD isoforms have not yet been solved. In this study, we describe structural models for soybean Cu/Zn SOD, Mn SOD and Fe SOD and provide insights into the molecular function of this metal-binding enzyme in improving tolerance to oxidative stress in plants. |
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| Keywords: | amino acid analysis model evaluation molecular modeling phylogenetic analysis superoxide dismutase (SOD) |
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