The effect of substituting carnitine for choline in the nutrition of several organisms |
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| Authors: | FRAENKEL G S FRIEDMAN S HINTON T LASZLO S NOLAND J L |
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| Affiliation: | 1. Centre for Wildlife Ecology, Simon Fraser University, 8888 University Drive, Burnaby, BC V5A 1S6, Canada;2. US Geological Survey, Alaska Science Center, 4210 University Drive, Anchorage, AK 99508, USA;3. Science and Technology Branch, Environment and Climate Change Canada, 5421 Robertson Road, Delta, BC V4K 3N2, Canada;4. Stantec Consulting Ltd., 2042 Mills Rd W, Sidney, BC V8L 5X4, Canada;5. Centre for Wildlife Ecology, Simon Fraser University, 8888 University Drive, Burnaby, BC V5A 1S6, Canada |
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| Abstract: | The effect of carnitine as a substitute for choline in the nutrition of four organisms that require a dietary supply of choline has been tested. Of these, a choline-less mutant of Neurospora crassa, the German cockroach Blatella germanica, and a flour beetle Palorus ratzeburgi failed to respond to carnitine. Carnitine had a very weak choline effect for the beetle Lasioderma serricorne. Drosophila melanogaster utilized carnitine in the place of and as well as choline, although growth was slightly slower. |
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