High-conductance pathways in mitochondrial membranes |
| |
Authors: | Oscar Moran M. Catia Sorgato |
| |
Affiliation: | (1) Laboratorio di Neurofisiologia, Scuola Internazionale Superiore di Studi Avanzati, Via Beirut 2/4, 134014 Trieste, Italy;(2) Dipartimento di Chimica Biologica, Universitá di Padova e Centro CNR per lo Studio della Fisiologia Mitocondriale, Via Trieste 75, 135121 Padova, Italy |
| |
Abstract: | The outer and inner membranes of mitochondria have recently been studied with the patch clamp technique. What has emerged is still an ill-defined picture for either membrane, primarily for the wide range of conductances found. Interestingly, however, a few conductances (in the range of 10–80 pS) seem to be ubiquitously distributed. Parallel studiesin situ and in reconstituted systems have allowed the assignment to distinct membrane locations of some conductances, whose physiological role is, however, not yet elucidated. |
| |
Keywords: | Channels intracellular membrane channels mitochondrial channels patch clamp |
本文献已被 SpringerLink 等数据库收录! |
|