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Human Immunodeficiency Virus,Antiretroviral Therapy and Markers of Lymphatic Filariasis Infection: A Cross-sectional Study in Rural Northern Malawi
Authors:Terence Tafatatha  Miriam Taegtmeyer  Bagrey Ngwira  Amos Phiri  Mariot Kondowe  Wilson Piston  Anna Molesworth  Ndoliwe Kayuni  Olivier Koole  Amelia Crampin  John Horton  Neil French
Abstract:BackgroundLymphatic filariasis (LF) and human immunodeficiency virus (HIV) are major public health problems. Individuals may be co-infected, raising the possibility of important interactions between these two pathogens with consequences for LF elimination through annual mass drug administration (MDA).Conclusions/SignificanceIn this large cross-sectional study of two distinct LF-exposed populations, there is no evidence that HIV infection has an impact on LF epidemiology that will interfere with LF control measures. A significant association of ART use with lower CFA prevalence merits further investigation to understand this apparent beneficial impact of ART.
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