Structure and function of the NS1 protein of influenza A virus |
| |
| Authors: | Lin Dongzi Lan Jingfang Zhang Zhizhen |
| |
| Institution: | Department of Biochemistry and Molecular Biology, Guangdong Medical College, Zhanjiang, China. |
| |
| Abstract: | The avian influenza A virus currently prevailing in Asia causes fatal pneumonia and multiple organ failure in birds and humans.Despite intensive research,understanding of the characteristics of influenza A virus that determine its virulence is incomplete.NS1A protein,a non-structural protein of influenza A virus,was reported to contribute to its pathogenicity and virulence.NS1A protein is a multifunctional protein that plays a significant role in resisting the host antiviral response during the influenza infection.This review briefly outlines the current knowledge on the structure and function of the NS1A protein. |
| |
| Keywords: | influenza A virus NS1A protein RNA-binding domain effector domain dimer resistance antiviral response |
| 本文献已被 CNKI 维普 PubMed 等数据库收录！ |
