Aurora Mitochondrialis drives fission during mitosis |
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| Authors: | Maia Ana Rita Maiato Helder |
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| Affiliation: | Chromosome Instability and Dynamics Laboratory, Instituto de Biologia Molecular e Celular, Universidade do Porto, Rua do Campo Alegre 823, 4150-180 Porto, Portugal. |
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| Abstract: | Mitochondria proliferate by growth and partition during every cell-division cycle. Recently, Kashatus et?al. (2011) reported that Aurora A kinase regulates the small GTPase RalA to mediate mitochondrial fission. This work illuminates the molecular mechanism behind mitochondrial inheritance in mammals and extends the functional repertoire of a key mitotic regulator. |
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