1.INSERM UMR 639, Université de la Méditerranée,Marseille,France;2.Assistance Publique, H?pitaux de Marseille, Rheumatology,La Conception Hospital,Marseille,France
Abstract:
The factors that trigger the development of extraarticular features of rheumatoid arthritis (RA) are still unknown. HLA-DR alleles such as HLA-DR4 and HLA-DR1 are associated with the risk to develop RA. A large scale study from Sweden and the Mayo Clinic suggests that HLA-DR4, but not HLA-DR1, is associated with the risk to develop extraarticular RA.
