Plasmacytoma of the breast. A report of two cases diagnosed by aspiration biopsy |
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Authors: | Cangiarella J Waisman J Cohen J M Chhieng D Symmans W F Goldenberg A |
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Affiliation: | Department of Pathology, New York University School of Medicine, New York, USA. joan.cangiarella@ccmail.med.nyu.edu |
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Abstract: | BACKGROUND: Extramedullary plasmacytoma of the breast is an uncommon neoplasm, occurring either as a solitary tumor or as evidence of disseminated multiple myeloma. CASE: Two cases of plasmacytoma of the breast were diagnosed by fine needle aspiration cytology. Aspiration smears showed a dispersed population of plasmacytoid cells with eccentric nuclei, abundant cytoplasm and the characteristic paranuclear hof. CONCLUSION: The clinical, cytologic and immunophenotypic features of plasmacytoma are characteristic, and the importance of distinguishing these neoplasms from primary mammary tumors is important to avoid unnecessary surgery. |
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