| RNA干扰抗病毒感染 |
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| 引用本文： | 孙剑. RNA干扰抗病毒感染[J]. 生物技术通讯, 2004, 15(1): 63-64 |
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| 作者姓名： | 孙剑 |
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| 作者单位： | 天津大学,药物科学与技术学院,天津,300072 |
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| 摘 要： | RNA干扰是由双链RNA诱导的、关闭同源序列基因表达的机制。它是一种自然存在于植物、线虫、果蝇等真核细胞生物中的抵抗病毒感染方式。随着在哺乳动物细胞培养中成功地诱导RNA干扰，利用RNA干扰预防、治疗病毒感染已成为新的研究热点，并取得了有希望的成果。在未来，有望成为抗病毒感染的有效方法。
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| 关 键 词： | RNA干扰 小干扰RNA 病毒 感染 |
| 文章编号： | 1009-0002(2004)01-0063-02 |
| 修稿时间： | 2003-06-19 |
RNA interference against virus infections |
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| SUN Jian College of Pharmaceuticals Science and Technology,Tianjin University,Tianjin,China. RNA interference against virus infections[J]. Letters in Biotechnology, 2004, 15(1): 63-64 |
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| Authors: | SUN Jian College of Pharmaceuticals Science Technology Tianjin University Tianjin China |
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| Affiliation: | SUN Jian College of Pharmaceuticals Science and Technology,Tianjin University,Tianjin300072,China |
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| Abstract: | RNA interference(RNAi)is induced by double-stranded RNA and silences the expression of homologous gene.It is a native anti-virus mechanism in plants,C.elegans,Drosophilae.After RNAi was successfully induced in mammalian cells,it became a hot research area to use RNAi in preventing and treating virus infection,and promising results had been achieved.In the future,RNAi may be a new therapeutic approach against virus infection in human. |
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| Keywords: | RNA interference small interfering RNA virus infection |
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