Selection of silk-binding peptides by phage display |
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Authors: | Nomura Yoko Sharma Vandana Yamamura Asami Yokobayashi Yohei |
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Institution: | (1) Department of Biomedical Engineering, University of California, Davis, 451 Health Sciences Drive, Davis, CA 95616, USA; |
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Abstract: | Peptides that bind to silkworm-derived silk fibroin fiber were selected from a phage-displayed random peptide library. The
selected silk-binding peptides contained a consensus sequence QSWS which is important for silk-binding as confirmed by binding
assays using phage and synthetic peptides. With further optimization, we anticipate that the silk-binding peptides will be
useful for functionalization of silk for biomaterial applications. |
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Keywords: | |
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