Resistance to tumor growth in guinea pigs immunized with lyophilized tumor cells |
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| Authors: | E Yarkoni B Zbar H J Rapp |
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| Institution: | (1) Laboratory of Immunobiology, National Cancer Institute, National Institutes of Health, 20014 Bethesda, Maryland, USA |
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| Abstract: | Summary Living BCG, killed Mycobacterium tuberculosis cells, or BCG cell walls (CW) augmented the immunogenicity of lyophilized syngeneic ascites hepatoma (line 10) of strain-2 guinea pigs. Effective vaccine contained living BCG and lyophilized line-10 cells, or mycobacterial cells or CW attached to oil droplets and lyophilized line-10 cells. Protection against the challenge tumor was evident 14 or 21 days after one administration of either vaccine. |
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