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Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis
Authors:Xiaoyan Zhao  Nwora Lance Okeke  Orr Sharpe  Franak M Batliwalla  Annette T Lee  Peggy P Ho  Beren H Tomooka  Peter K Gregersen  William H Robinson
Affiliation:(1) GRECC, VA Palo Alto Health Care System, 94304, 3801 Miranda Avenue, Palo Alto, CA, USA;(2) Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, 94305, 269 Campus Drive West, Stanford, CA, USA;(3) Robert S. Boas Center for Genomics and Human Genetics, Feinstein Institute for Medical Research, 11030, 350 Community Drive, Manhasset, NY, USA;(4) Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 94305, 269 Campus Drive West, Stanford, CA, USA
Abstract:

Introduction  

There is increasing evidence that autoantibodies and immune complexes (ICs) contribute to synovitis in rheumatoid arthritis (RA), yet the autoantigens incorporated in ICs in RA remain incompletely characterised.
Keywords:
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