Inside Back Cover: Optimizing interstitial photodynamic therapy with custom cylindrical diffusers (J. Biophotonics 1/2019)

Interstitial photodynamic therapy (iPDT) planning aims to minimize the damage to organs‐at‐risk (OAR), while maximizing dose coverage of the tumor by optimizing the number of light diffusers, their positions and their allocated powers. The cover describes a new degree of freedom to optimize upon in iPDT, namely diffusers' power emission profiles. The tool generates manufacturable customized emission profiles that lead to better conformation to brain tumor shapes, resulting in 50% further minimization of damage to OAR. Background image is taken from the National Cancer Institute (NCI). Further details can be found in the article by Abdul‐Amir Yassine, Lothar Lilge, and Vaughn Betz ( e201800153 ).