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Potent Antiproliferative Effects of 25‐Hydroxy‐16‐ene‐23‐yne‐vitamin D3 That Resists the Catalytic Activity of Both CYP27B1 and CYP24A1
Authors:Steve Y Rhieu  Andrew J Annalora  Erika LaPorta  JoEllen Welsh  Toshimasa Itoh  Keiko Yamamoto  Toshiyuki Sakaki  Tai C Chen  Milan R Uskokovic  G Satyanarayana Reddy
Institution:1. Epimer LLC, North Smithfield, Rhode Island, USA;2. Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, Oregon, USA;3. Cancer Research Center and Departments of Biomedical Sciences and Environmental Health Sciences, University at Albany, Rensselaer, New York, USA;4. Laboratory of Drug Design and Medicinal Chemistry, Showa Pharmaceutical University, Tokyo, Japan;5. Department of Biotechnology, Faculty of Engineering, Toyama Prefectural University, Imizu, Japan;6. School of Medicine, Boston University, Boston, Massachusetts, USA;7. Hoffmann‐La Roche Inc., Nutley, New Jersey, USA
Abstract:
Keywords:VITAMIN D  16‐ene‐23‐yne  CYP27B1  CYP24A1  ANTIPROLIFERATIVE ACTIVITY
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