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Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope
Authors:Goran Bajic  Max J. Maron  Yu Adachi  Taishi Onodera  Kevin R. McCarthy  Charles E. McGee  Gregory D. Sempowski  Yoshimasa Takahashi  Garnett Kelsoe  Masayuki Kuraoka  Aaron G. Schmidt
Affiliation:1. Laboratory of Molecular Medicine, Boston Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA;2. Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA;3. Department of Immunology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan;4. Duke Human Vaccine Institute, Duke University, Durham, NC 27710, USA;5. Department of Immunology, Duke University, Durham, NC 27710, USA;6. Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA
Abstract:
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  • Keywords:Corresponding author  immunogen design  protein engineering  broadly neutralizing antibodies  influenza hemagglutinin
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