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A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis
Authors:Sanghyun Lee  Hejun Liu  Craig B. Wilen  Zoi E. Sychev  Chandni Desai  Barry L. Hykes  Robert C. Orchard  Broc T. McCune  Ki-Wook Kim  Timothy J. Nice  Scott A. Handley  Megan T. Baldridge  Gaya K. Amarasinghe  Herbert W. Virgin
Affiliation:1. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA;2. Departments of Laboratory Medicine and Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA;3. Department of Immunology, the University of Texas Southwestern Medical Center, Dallas, TX 75390, USA;4. Department of Pharmacology and Center for Stem Cell and Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL 60612, USA;5. Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239, USA;6. Department of Medicine, Division of Infectious Diseases, Edison Family Center for Genome Sciences & Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA
Abstract:
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  • Keywords:Corresponding author  norovirus  vaccine  secretion  NS1  IFN-λ
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