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Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1
Authors:Shaonan Liang  Xue-Kun Guo  Jiayao Ou  Rongyao Huang  Qing Xue  Bin Zhang  Yeonseok Chung  Wei Wu  Chen Dong  Xuerui Yang  Xiaoyu Hu
Institution:1. Institute for Immunology and School of Medicine, Tsinghua University, Beijing 100084, China;2. Beijing Key Laboratory for Immunological Research on Chronic Diseases, Tsinghua University, Beijing 100084, China;3. Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China;4. MOE Key Laboratory of Bioinformatics, Center for Synthetic & Systems Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China;5. MOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing 100084, China;6. Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, South Korea;7. Collaborative Innovation Center for Biotherapy, Tsinghua University, Beijing 100084, China
Abstract:
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  • Keywords:Corresponding author  antimicrobial proteins  α-defensins  Hes1  enteric infection  nutrient sensing  intestinal epithelial cell
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