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应加强对单细胞生物分批培养生长曲线中减速期的认识和教学
引用本文:邱立友,王明道,宋安东,张世敏,刘新育,高玉千,戚元成.应加强对单细胞生物分批培养生长曲线中减速期的认识和教学[J].微生物学通报,2008,35(3):0432-0435.
作者姓名:邱立友  王明道  宋安东  张世敏  刘新育  高玉千  戚元成
作者单位:河南农业大学生命科学学院,郑州,450002
摘    要:根据单细胞生物分批培养过程中比生长速率(μ)的变化,其生长曲线分为延滞期、加速期、对数期、减速期、稳定期和衰亡期6个时期.与其他生长时期相比,在减速期生物的生长、基质的利用、产物的合成和基因表达谱等方面有显著的不同,并对发酵生产有着重要作用.然而,长期以来,对减速期的认识和教学相当薄弱,亟需加强对减速期的认识和教学.

关 键 词:单细胞生物  分批培养生长曲线  减速期  生长动力学  产物合戍  基因表达谱  加强  单细胞  生物  分批培养  生长曲线  认识  教学  Cultivation  Batch  Curve  Growth  Single  Cell  Phase  Deceleration  Teaching  作用  发酵生产  基因表达谱  合成  利用
修稿时间:2007年8月1日

Should Strengthen Cognizing and Teaching to the Deceleration Phase of Single Cell Organisms Growth Curve in Batch Cultivation
QIU Li-You,WANG Ming-Dao,SONG An-Dong,ZHANG Shi-Min,LIU Xin-Yu,GAO Yu-Qian and QI Yuan-Cheng.Should Strengthen Cognizing and Teaching to the Deceleration Phase of Single Cell Organisms Growth Curve in Batch Cultivation[J].Microbiology,2008,35(3):0432-0435.
Authors:QIU Li-You  WANG Ming-Dao  SONG An-Dong  ZHANG Shi-Min  LIU Xin-Yu  GAO Yu-Qian and QI Yuan-Cheng
Institution:College of Life Science, Henan Agricultural University, Zhengzhou 450002;College of Life Science, Henan Agricultural University, Zhengzhou 450002;College of Life Science, Henan Agricultural University, Zhengzhou 450002;College of Life Science, Henan Agricultural University, Zhengzhou 450002;College of Life Science, Henan Agricultural University, Zhengzhou 450002;College of Life Science, Henan Agricultural University, Zhengzhou 450002;College of Life Science, Henan Agricultural University, Zhengzhou 450002
Abstract:The growth curve of single cell organisms in batch cultivation could divide into 6 phases, lag phase, acceleration phase, log phase, deceleration phase, stationary phase, and death phase, based on specific growth rate during cultivation process. There were significantly differences between deceleration phase and the other phases in cell growth, substrate consumption, product formation, and genes express profile. The deceleration phase was highly important to fermentation process. However, cognizing and teaching to the deceleration phase had been considerably weakened since a long period. So it should be strengthened.
Keywords:Single cell organisms  Growth curve in batch cultivation  Deceleration phase  Growth kinetics  Product formation  Genes express profile
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