1. Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, ul. Institutskaya 3, Pushchino, 142290, Russia 2. Pushchino State Institute of Natural Sciences, pr. Nauki 3, Pushchino, 142290, Russia
Abstract:
The effect of portacaval shunting on the antioxidant status of the cerebellum and hippocampus has been studied in rats using standard methods of enzymatic analysis. Endogenous ammonia levels and activities of eight antioxidant enzymes were shown to be unequal in these two brain regions and to respond differently to intrahepatic portosystemic shunt surgery.