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Body Weight-Supported Treadmill Training Ameliorates Motoneuronal Hyperexcitability by Increasing GAD-65/67 and KCC2 Expression via TrkB Signaling in Rats with Incomplete Spinal Cord Injury
Authors:Li  Xiangzhe  Song  Xinjian  Fang  Lu  Ding  Jie  Qi  Longju  Wang  Qinghua  Dong  Chuanming  Wang  Sheng  Wu  Jiahuan  Wang  Tong  Wu  Qinfeng
Institution:1.Rehabilitation Medical Center, Suzhou Science & Technology Town Hospital, Gusu School, Nanjing Medical University, No.1 Lijiang Road, Suzhou, 215153, Jiangsu, People’s Republic of China
;2.Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, No.300 Guangzhou Road, Nanjing, 210029, Jiangsu, People’s Republic of China
;3.Department of Rehabilitation Medicine, Affiliated Nantong Rehabilitation Hospital of Nantong University, Nantong, 226002, Jiangsu, People’s Republic of China
;4.Department of Rehabilitation Medicine, The Second People’s Hospital of Nantong, Nantong, 226002, Jiangsu, People’s Republic of China
;5.Departments of Respiratory Care, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, 310016, Zhejiang, People’s Republic of China
;6.Department of Orthopaedics, Affiliated Nantong Hospital 3 of Nantong University, Nantong, 226001, Jiangsu, People’s Republic of China
;7.Experimental Animal Center, Nantong University, No.19 Qixiu Road, Nantong, 226001, Jiangsu, People’s Republic of China
;8.Department of Anatomy, Medical College of Nantong University, No.19 Qixiu Road, Nantong, 226001, Jiangsu, People’s Republic of China
;
Abstract:Neurochemical Research - Spasticity is a typical consequence after spinal cord injury (SCI). The critical reasons are reducing the synthesis of Gamma-Aminobutyric Acid (GABA), glycine and potassium...
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