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Effect of P-glycoprotein Inhibition on the Penetration of Ceftriaxone Across the Blood–Brain Barrier |
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| Authors: | Shan Yuheng Cen Yuying Zhang Yanjin Tan Ruishu Zhao Jiahua Nie Zhiyong Zhang Jiatang Yu Shengyuan |
| Institution: | 1.Medical School of Chinese PLA, Beijing, 100853, People’s Republic of China ;2.Department of Neurology, The First Medical Centre, Chinese PLA General Hospital, No. 28, Fuxing Road, Beijing, 100853, People’s Republic of China ;3.Department of Neurology, Characteristic Medical Centre of People’s Armed Police Force, Tianjin, 300162, People’s Republic of China ;4.State Key Laboratory of Toxicology and Medical Countermeasures, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing, 100850, People’s Republic of China ; |
| Abstract: | Neurochemical Research - Recent studies indicate that inhibition of the efflux transporter P-glycoprotein (P-gp) at the blood–brain barrier (BBB) may represent a putative strategy to increase... |
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