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Spermine synthesis inhibitor blocks 25-hydroxycholesterol-induced- apoptosis via SREBP2 upregulation in DLD-1 cell spheroids
Authors:Miku Kakimoto  Hideya Yamamoto  Arowu R Tanaka
Abstract:
Keywords:25-Hydroxycholesterol  Polyamine  DFMO  APCHA  SREBP2  25-HC"}  {"#name":"keyword"  "$":{"id":"kwrd0040"}  "$$":[{"#name":"text"  "_":"25-hydroxycholesterol  SREBP2"}  {"#name":"keyword"  "$":{"id":"kwrd0050"}  "$$":[{"#name":"text"  "_":"sterol regulatory element binding protein 2  SCAP"}  {"#name":"keyword"  "$":{"id":"kwrd0060"}  "$$":[{"#name":"text"  "_":"SREBP cleavage activating protein  INSIG"}  {"#name":"keyword"  "$":{"id":"kwrd0070"}  "$$":[{"#name":"text"  "_":"insulin inducing gene  S1P"}  {"#name":"keyword"  "$":{"id":"kwrd0080"}  "$$":[{"#name":"text"  "_":"site-1 protease  S2P"}  {"#name":"keyword"  "$":{"id":"kwrd0090"}  "$$":[{"#name":"text"  "_":"site-2 protease  poly-HEMA"}  {"#name":"keyword"  "$":{"id":"kwrd0100"}  "$$":[{"#name":"text"  "_":"poly-(2-hydroxyethyl methacrylate)  MTT"}  {"#name":"keyword"  "$":{"id":"kwrd0110"}  "$$":[{"#name":"text"  "_":"3-[4  5-dimethylthiazol-2-yl]-2  5-diphenyltetrazolium bromide  DFMO"}  {"#name":"keyword"  "$":{"id":"kwrd0120"}  "$$":[{"#name":"text"  "_":"difluoromethylornithine  APCHA"}  {"#name":"keyword"  "$":{"id":"kwrd0130"}  "$$":[{"#name":"text"  "_":"N-(3-Aminopropyl)cyclohexylamine  SRE"}  {"#name":"keyword"  "$":{"id":"kwrd0140"}  "$$":[{"#name":"text"  "_":"sterol response element  HMG-CoA"}  {"#name":"keyword"  "$":{"id":"kwrd0150"}  "$$":[{"#name":"text"  "_":"3-hydroxy-3-methylglutaryl-coenzyme A
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