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Knockdown of Piccolo in the Nucleus Accumbens Suppresses Methamphetamine-Induced Hyperlocomotion and Conditioned Place Preference in Mice |
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| Authors: | Kusui Yuka Izuo Naotaka Uno Kyosuke Ge Bin Muramatsu Shin-ichi Nitta Atsumi |
| Affiliation: | 1.Department of Pharmaceutical Therapy and Neuropharmacology, Faculty of Pharmaceutical Sciences, University of Toyama, Toyama, Japan ;2.Laboratory of Molecular Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Hirakata, Japan ;3.Division of Neurological Gene Therapy, Center for Open Innovation, Jichi Medical University, Shimotsuke, Japan ;4.Center for Gene & Cell Therapy, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan ;5.Department of Pharmaceutical Therapy and Neuropharmacology, School of Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan ; |
| Abstract: | Neurochemical Research - Methamphetamine (METH), the most widely distributed psychostimulant, aberrantly activates the reward system in the brain to induce addictive behaviors. The presynaptic... |
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