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Oleuropein Protects Against Cerebral Ischemia Injury in Rats: Molecular Docking,Biochemical and Histological Findings
Authors:Mnafgui  Kais  Ghazouani  Lakhdar  Hajji  Raouf  Tlili  Abir  Derbali  Fatma  da Silva  Francisco Ivan  Araújo  Joabe Lima  de Oliveira Schinoff  Bianca  Bachega  José Fernando Ruggiero  da Silva Santos  Antônia Laíres  Allouche   Noureddine
Affiliation:1.Laboratory of Animal Physiology, Faculty of Sciences of Sfax, University of Sfax, P.O. Box 95, 3052, Sfax, Tunisia
;2.Research Unit of Macromolecular Biochemistry and Genetics, Faculty of Sciences of Gafsa, University of Gafsa, 2112, Gafsa, Tunisia
;3.Service de Médecine Interne, Faculté de Médecine de Sousse, H?pital de Sidi Bouzid, Université de Sousse, Sidi Bouzid 9100, 4200, Sousse, Tunisia
;4.Faculty of Medicine of Monastir, 5000, Monastir, Tunisia
;5.Department of Chemistry, Center for Natural Sciences, Federal University of Piauí, Campus Ministro Petr?nio Portela, 64049-550, Teresina, PI, Brazil
;6.Programa de Pós-Gradua??o em Nanociência e Nanobiotecnologia, Departamento de Genética e Morfologia, Universidade de Brasília, s/n Campus Universitário Darcy Ribeiro, 70910-900, Brasília, DF, Brasil
;7.Departamento de Farmacociências, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil
;8.Programa de pós-gradua??o em Biologia Celular e molecular, Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
;9.Laboratory of Organic Chemistry LR17ES08 (Natural Substances Team), Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia
;
Abstract:Neurochemical Research - This study was designed to evaluate the underlying protective mechanisms of oleuropein involved in alleviating brain damage in a rat model of ischemic stroke. Male Wistar...
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