原发性小肠淋巴瘤6例临床分析并文献复习

目的:探讨原发性小肠淋巴瘤临床特点,诊断及治疗方法。方法:对1997-2012年确诊的6例原发性小肠淋巴瘤患者的临床资料进行临床分析,总结其临床特点,同时复习相关文献。结果:隐性失血、脐周隐痛、腹部肿物、隐匿消瘦是原发性小肠淋巴瘤的最常见表现,而以全身症状为主的很少。推进式小肠镜及胶囊内镜的应用对该病诊断有重要价值,但阳性率较低。MSCT和MRE对本病的诊断有重要辅助作用。本组患者病理结果均为非霍奇金淋巴瘤,其中B细胞型4例,T细胞型2例,4例发生淋巴转移。6例患者中4例行手术切除治疗,2例行单纯化疗,2例死亡。结论:选择有效的检查手段,可提高小肠肿瘤的术前诊断,降低其误诊误治的发生率。手术切除是治疗该疾病的主要手段,采用手术后配合化疗及放疗的综合治疗可提高患者的生存率。

Primary Lymphomas of the Small Intestine: a Report of 6 Cases and Review of Literature

Objective: To investigate the clinical characteristics, diagnosis and therapy of primary lymphoma in the small intestine. Methods: The clinical data of 6 cases with primary small intestine lymphoma from 1997 to 2012 were retrospectively studied, and the clinical features were summarized. At the same time a review of literature was made.Results:The main clinical features of these patients consisted of occult bleeding in digestive tract, mild abdominal pain, abdominal mass and gradual losing of body weight. However, the positive rate is lower. It play important role in support of the diagnosis of this disease for MSCT and MRE. The postoperative pathology of all the patients wasnon- Hodgkin''s lymphoma, 4 were B cell type, 2 were T cell type. There were 4 cases with regional node metastases by pathologic examination. 4 cases were maken surgical resection, 2 were maken Chemotherapy, 2 deaths. Conclusion:The effective inspection method can improve the preoperative diagnosis of small intestinal tumor, and reduce the incidence of the disease diagnosis. Operation treatment is the main method of the disease, after the surgery with chemotherapy and radiotherapy treatment can improve the survival rate of patients.