蜜蜂抗菌肽研究及其应用进展

抗菌肽是一类由特定基因编码的小分子多肽，广泛分布于各种生物中，是生物天然免疫的重要效应分子，其对缺乏获得性免疫系统的昆虫尤为重要。蜜蜂是一种对环境极其重要的社会性模式昆虫，又有着极高的经济价值，因此蜜蜂抗菌肽有着较大的研究意义。本文对蜜蜂4种天然免疫抗菌肽(Apidaecin、Abaecin、Hymenoptaecin和Defensin)和蜂产品中的抗菌肽(Jelleines、Melittin和Apamin)研究进展进行了综述，介绍了它们的功能、作用机制及其应用，提出了蜜蜂抗菌肽未来可行的研究方向，旨在推动蜜蜂抗菌肽的研究。

Research and application progress of bee antimicrobial peptides

Antimicrobial peptides (AMPs) are a class of peptides with low molecular weight, which are encoded by specific genes of organisms and are important effectors of natural immunity of organisms, especially for insects lacking acquired immune system. Honeybee is a social model insect which is very important to the environment, and it has high economic value. Therefore, honeybee antimicrobial peptide has great significance. In this paper, the research progress of four kinds of bee natural immune antimicrobial peptides (apidaecin, abaecin, hymenoptaecin and defensin) and antimicrobial peptides in bee products (jelleines, melittin and apamin) were reviewed. Their functions, mechanisms of action and applications were introduced. The future research directions of bee antimicrobial peptides were put forward to promoting the research of bee antimicrobial peptides.