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Indications for an early invasive strategy in NSTE-ACS patients
Authors:Zwart  B.  ten Berg  J. M.  van ’t Hof  A. W.  Tonino  P. A. L.  Appelman  Y.  Liem  A. H.  Arslan  F.  Waltenberger  J.  Jukema  J. W.  de Winter  R. J.  Damman  P.
Affiliation:1.Department of Cardiology, Catharina ziekenhuis, Eindhoven, The Netherlands
;2.Department of Cardiology, St. Antonius ziekenhuis, Nieuwegein, The Netherlands
;3.Department of Cardiology, Maastricht University Medical Center (UMC)+, Maastricht, The Netherlands
;4.Department of Cardiology, Amsterdam University Medical Center, Location VU University Medical Center, Amsterdam, The Netherlands
;5.Department of Cardiology, Franciscus Gasthuis, Rotterdam, The Netherlands
;6.Department of Cardiovascular Medicine, Medical Faculty, University of Münster, Münster, Germany
;7.Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
;8.Department of Cardiology, Amsterdam University Medical Center, location AMC, University of Amsterdam, Amsterdam, The Netherlands
;9.Department of Cardiology, Radboud University Medical Center, Nijmegen, The Netherlands
;
Abstract:

An early invasive strategy in patients who have acute coronary syndrome without ST-elevation (NSTE-ACS) can improve clinical outcome in high-risk subgroups. According to the current guidelines of the European Society of Cardiology (ESC), the majority of NSTE-ACS patients are classified as “high-risk”. We propose to prioritise patients with a global registry of acute coronary events (GRACE) risk score >140 over patients with isolated troponin rise or electrocardiographic changes and a GRACE risk score <140. We also acknowledge that same-day transfer for all patients at a high risk is not necessary in the Netherlands since the majority of Dutch cardiology departments are equipped with a catheterisation laboratory where diagnostic coronary angiography is routinely performed in NSTE-ACS patients. Therefore, same-day transfer should be restricted to true high-risk patients (in addition to those NSTE-ACS patients with very high-risk (VHR) criteria) in centres without coronary angiography capabilities.

Keywords:
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