Immunocytochemical demonstration of tubulin microheterogeneity within rat cortical and hippocampal pyramidal neurons |
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Authors: | F Hajós K Gallatz |
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Institution: | (1) First Department of Anatomy, Semmelweis University Medical School, Tüzoltó u. 58, H-1450 Budapest, Hungary |
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Abstract: | Summary Rat cortical and hippocampal pyramidal cells were immunocytochemically investigated using the TU-01 monoclonal antibody recognizing
α-tubulin. The isotypic specificity of this antibody is distinct from that of other available α-tubulin antibodies; therefore,
an intracellular heterogeneity among neuronal microtubules could be revealed by observing intensely immunostained apical dendritic
microtubules in the complete absence of staining of the microtubules in the basal dendrites and perikarya of the same pyramidal
cells. |
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Keywords: | |
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