| The role of γ-aminobutyric acid and its receptors in the nucleus of basal optic root in pigeons |
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| 引用本文： | 付煜西,高宏峰,王书荣,Stephen A.George.The role of γ-aminobutyric acid and its receptors in the nucleus of basal optic root in pigeons[J].中国科学：生命科学英文版,1997(3). |
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| 作者姓名： | 付煜西 高宏峰 王书荣 Stephen A.George |
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| 作者单位： | Laboratory for Visual Information Processing，Institute of Biophysics，Chinese Academy of Sciences Beijing 100101，China，Laboratory for Visual Information Processing，Institute of Biophysics，Chinese Academy of Sciences Beijing 100101，China，Laboratory for Visual Information Processing，Institute of Biophysics，Chinese Academy of Sciences Beijing 100101，China，Department of Biology，Amherst College，MA 01002 - 5000，USA. |
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| 基金项目： | Project supported by the National Natural Science Foundation of China and Amherst College. |
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| 摘 要： | The effects of γ-aminobutyric acid (GABA) and its antagonists bicuculline and 2-hydroxysaclofen on neuronal firings in the nucleus of basal optic root (nBOR) in pigeons were studied by using extracellular recording and microiontophoretic techniques. The results suggest that GABA may be an inhibitory neurotransmitter or modulator within nBOR, functioning by means of main mediation of GABAA receptors and of minor mediation of GABAB receptors. Furthermore, GABA and its GABAA receptors are involved in the modulation of directional selectivity in part of nBOR neurons.
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| 关 键 词： | nucleus or basal optic root (nBOR) microiontophoresis γ-aminobutyric acid (GABA) receptor inhibition pigeon. |
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