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A Symmetric Extended Logistic Model with Applications to Experimental Toxicity Data
Authors:Mohammed A. El-Saidi
Abstract:The fit of the logit and probit models for quantal response data can be improved by embedding these classical models within a richer parametric family indexed by one or two shape parameters. In this paper, a symmetric extended logistic model indexed by a shape parameter λ is discussed with application to dose response curves. The usual maximum likelihood method is employed to estimate the parameters of the model. The need to include the shape parameter λ is illustrated by analyzing a set of real experimental data and comparing the fit of the extended logistic model to those obtained by the standard logit and probit models.
Keywords:Bioassay  Quantal response data  Dose response curve model  Shape parameters  Logit model  Probit model  Maximum likelihood estimates
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