| GABA和苦毒素等药物对螽斯听觉中间神经元AN2声反应特征的影响 |
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| 引用本文： | 于琦,沈钧贤.GABA和苦毒素等药物对螽斯听觉中间神经元AN2声反应特征的影响[J].生物物理学报,1994,10(4):597-600. |
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| 作者姓名： | 于琦 沈钧贤 |
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| 作者单位： | 中国科学院生物物理研究所 |
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| 摘 要： | 利用单细胞电生理记录技术，观测了在前胸施加ＧＡＢＡ、苦毒素和筒箭毒等药物对螽斯Ｇａｍｐｏｃｌｅｉｓｇｒａｔｉｏｓａ听觉上升神经元ＡＮ２的声反应放电活动的影响。发现ＧＡＢＡ和筒箭毒都能抑制ＡＮ２的放电活动，而苦毒素则将其放电模式变为“ｔｏｎｉｃ”型。
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| 关 键 词： | 听觉中间神经元，GABA，苦毒素，筒箭毒，螽斯 |
THE EFFECTS OF GABA AND PICROTOXIN ON THE RESPONSE CHARACTERISTICS OF AUDITORY INTERNEURON AN2 IN BUSHCRICKET Gampsocleis gratiosa |
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| Yu Qi, Shen Junxian.THE EFFECTS OF GABA AND PICROTOXIN ON THE RESPONSE CHARACTERISTICS OF AUDITORY INTERNEURON AN2 IN BUSHCRICKET Gampsocleis gratiosa[J].Acta Biophysica Sinica,1994,10(4):597-600. |
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| Authors: | Yu Qi Shen Junxian |
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| Abstract: | Intracellular electrophysiological technique was used to detect the effects of GABA and its antagonist picrotoxin, and also d-tubocurarine on spike discharge characteristics of the auditory interneuron AN2 in the bushcricket Gampocleis gratiosa. The results show that GABA and d-tubocurarine inhibit spike discharge of AN2, While picrotoxin increases the spike discharge of the AN2 neuron, and even changes its discharge pattern from "Quasi-tonic" to "tonic". |
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| Keywords: | Auditory interneuron Bushcricket (Gampsocleis gratiosa )GABA Picrotoxin d -Tubocurarine |
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