Analysis of genetic variability in American Pit Bull Terrier breed of dogs with a high inbreeding level using microsatellite markers |
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Authors: | L. N. Shinkarenko O. G. Guliakova V. A. Malienko S. D. Melnychuk V. G. Spyrydonov |
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Affiliation: | 1. National University of Life and Environmental Science of Ukraine, Kiev, Ukraine 2. Ukrainian Laboratory of Quality and Safety of AIC, Kiev, Ukraine
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Abstract: | The level of DNA polymorphism in 10 microsatellite loci of 27 American Pit Bull Terrier dogs with high percentage of blood and inbreeding coefficients of up to 43.8% was studied. The observed heterozygosity was higher than expected for this inbreeding level. The presence of a selection mechanism that prevents gametes from fusing to form a homozygosity genotype is suggested. |
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