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Analysis of genetic variability in American Pit Bull Terrier breed of dogs with a high inbreeding level using microsatellite markers
Authors:L. N. Shinkarenko  O. G. Guliakova  V. A. Malienko  S. D. Melnychuk  V. G. Spyrydonov
Affiliation:1. National University of Life and Environmental Science of Ukraine, Kiev, Ukraine
2. Ukrainian Laboratory of Quality and Safety of AIC, Kiev, Ukraine
Abstract:The level of DNA polymorphism in 10 microsatellite loci of 27 American Pit Bull Terrier dogs with high percentage of blood and inbreeding coefficients of up to 43.8% was studied. The observed heterozygosity was higher than expected for this inbreeding level. The presence of a selection mechanism that prevents gametes from fusing to form a homozygosity genotype is suggested.
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