Protein misfolding and misprocessing in complex disease |
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Authors: | Fadiel A Eichenbaum K D Hamza A Tuncalp O Luk J Naftolin F |
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Affiliation: | Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, School of Medicine, New Haven, CT 06520, USA. afadiel@yale.edu |
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Abstract: | Scientists from over 20 major research centers recently convened to discuss advances and new discoveries in "Protein MisFolding and MisProcessing in Disease." Understanding protein mechanisms the underlying etiology of complex diseases lies in analyzing the associated biochemical mechanisms, which include folding patterns, processing patterns, chaperone regulators, stress pathways, and signal transduction. |
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