The appearance of a critical input concentration of fructose 6-phosphate in the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase cycle |
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Authors: | M Kretschmer W Schellenberger E Hofmann |
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Institution: | Institute of Biochemistry, Karl-Marx-University, Leipzig, German Democratic Republic. |
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Abstract: | Stationary states of the fructose 6-phosphate/fructose 2,6-bisphosphate cycle were investigated in relation to the input concentration of fructose 6-phosphate. Below a critical input concentration of fructose 6-phosphate very low levels of fructose 2,6-bisphosphate were obtained. Above this point the fructose 2,6-bisphosphate changes in direct proportion to the input of fructose 6-phosphate. Phosphorylation of the enzyme causes an increase of the critical input concentration of fructose 6-phosphate. The control coefficients for fructose 2,6-bisphosphate have their maximum at the critical input concentration of fructose 6-phosphate. |
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