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Synthesis and structure-activity relationships of novel nikkomycin analogs: inhibitors of the fungal cell wall biosynthesis enzyme chitin synthase. |
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| Authors: | J Uda K Obi K Iwase O Sugimoto H Ebisu A Matsuda |
| Institution: | Central Research Laboratories, Kyorin Pharmaceutical Co. Ltd., Tochigi-ken, Japan. |
| Abstract: | A series of novel nikkomycin analogs, which inhibited chitin synthase, the fungal cell wall biosynthesis enzyme, has been synthesized and evaluated their inhibitory activities. |
| Keywords: | |