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Carnosine, the Protective, Anti-aging Peptide
Authors:Alexander A Boldyrev  Steven Ch Gallant  Gennady T Sukhich
Institution:(1) Center for Molecular Medicine, Department of Biochemistry, Biological Faculty, MV Lomonosov, 0Moscow State University, Vorobjovy Gory, 119899 Moscow, Russia;;(2) Extend Foundation, Herts, CM23 3EF, England. UK;(3) Scientific Center for Obstetrics, Gynecology and Perinetology of Russian Academy of Medical Sciences, Moscow, Russia
Abstract:Carnosine attenuates the development of senile features when used as a supplement to a standard diet of senescence accelerated mice (SAM). Its effect is apparent on physical and behavioral parameters and on average life span. Carnosine has a similar effect on mice of the control strain, but this is less pronounced due to the non-accelerated character of their senescence processes.
Keywords:Carnosine  oxidative stress  aging  senescence accelerated mice (SAM)
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