Carnosine, the Protective, Anti-aging Peptide |
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Authors: | Alexander A Boldyrev Steven Ch Gallant Gennady T Sukhich |
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Institution: | (1) Center for Molecular Medicine, Department of Biochemistry, Biological Faculty, MV Lomonosov, 0Moscow State University, Vorobjovy Gory, 119899 Moscow, Russia;;(2) Extend Foundation, Herts, CM23 3EF, England. UK;(3) Scientific Center for Obstetrics, Gynecology and Perinetology of Russian Academy of Medical Sciences, Moscow, Russia |
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Abstract: | Carnosine attenuates the development of senile features when used as a supplement to a standard diet of senescence accelerated mice (SAM). Its effect is apparent on physical and behavioral parameters and on average life span. Carnosine has a similar effect on mice of the control strain, but this is less pronounced due to the non-accelerated character of their senescence processes. |
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Keywords: | Carnosine oxidative stress aging senescence accelerated mice (SAM) |
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