Manipulating dendritic cells to induce regulatory T cells |
| |
Authors: | Penna G Giarratana N Amuchastegui S Mariani R Daniel K C Adorini L |
| |
Affiliation: | BioXell, Milan, Italy. |
| |
Abstract: | Dendritic cells (DCs) induce and regulate T-cell responses, and tolerogenic DCs can promote the development of regulatory T cells with suppressive activity. The possibility of manipulating DCs using different pharmacological or biological agents, enabling them to exert tolerogenic activities, could be exploited to better control a variety of chronic inflammatory conditions, from autoimmune diseases to allograft rejection. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|