Toxigenicity and antimicrobial susceptibility ofClostridium difficile,a cause of antimicrobial agent-associated colitis |
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| Authors: | W Lance George Vera L Sutter Sydney M Finegold |
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| Institution: | (1) Infectious Disease Section, Research and Medical Services, Wadsworth Veterans Administration Hospital, 90073 Los Angeles, California, USA;(2) the Department of Medicine, University of California, Center for the Health Sciences, Los Angeles |
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| Abstract: | Fourteen of 16 strains ofClostridium difficile, a recently recognized cause of antimicrobial agent-associated ileocolitis in laboratory animals and colitis in man, were
found to be toxigenic. The susceptibility of these isolates to a variety of antimicrobial agents provides information that
may be of value in assessing the means by whichC. difficile may produce colitis, in developing selective bacteriologic media for diagnosis, and in selecting appropriate antimicrobial
therapy for colitis. |
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