Conductometric properties of human erythrocyte membranes: dependence on haematocrit and alkali metal ions of the suspending medium |
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Authors: | F Bordi C Cametti R Misasi R De Persio G Zimatore |
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Institution: | (1) Sezione di Fisica Medica, Dipartimento di Medicina Interna, Università di Roma ``Tor Vergata', I-00185 Rome, Italy, IT;(2) Dipartimento di Fisica, Università di Roma ``La Sapienza', Piazzale A. Moro 2, I-00185 Rome, Italy, IT;(3) Istituto Nazionale di Fisica della Materia (IFNM) Unita di Roma ``La Sapienza', I-00185 Rome, Italy, IT;(4) Dipartimento di Medicina Sperimentale, Universitá ``La Sapienza', I-00185 Rome, Italy, IT |
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Abstract: | The electrical properties of the cytoplasmatic membrane of human erythrocyte cells have been evaluated by means of dielectric
spectroscopy measurements in the radiowave frequency range, using the so-called ``suspension method'. Measurements have been
carried out at different volume fractions of the corpuscular phase (the cell haematocrit) in order to investigate the influence
of the cell-cell interactions on the electrical parameters (the membrane permittivity ε and the membrane conductivity σ) of the cell membrane and a set of new values are proposed. Moreover, the influence of different alkali metal ions (Na+, K+, Cs+, Li+) on the ion permeation properties of the membrane are investigated and the structural alterations in the membrane organized
briefly discussed.
Received: 29 October 1996 / Accepted: 13 March 1997 |
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Keywords: | Erythrocyte membrane Conductometric properties Ion permeation |
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