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Enhancement of growth and antibiotic titre inCephalosporium acremonium induced by sesame oil
Authors:S Paul  R L Bezbaruah  R S Prakasham  M K Roy  A C Ghosh
Institution:(1) Regional Research Laboratory Jorhat, Biochemistry Division, 785 006 Assam, India
Abstract:The role of sesame oil as part of the carbon source on growth and cephalosporin C production byCephalosporium acremonium was studied in shake-flask fermentation. The growth and antibiotic production were maximum on the fifth and sixth day, respectively, irrespective of the presence of sesame oil. Sesame oil enhanced cephalosporin C production by 54%. Analysis of fatty acid profile indicated that C18∶1, C18∶2 and C18∶3 are the major fatty acids inC. acremonium. The percentage of C18∶2 was higher in the culture grown with sesame oil.
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