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Compound C sensitizes Caki renal cancer cells to TRAIL-induced apoptosis through reactive oxygen species-mediated down-regulation of c-FLIPL and Mcl-1 |
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| Authors: | Ji Hoon Jang Eun Sun Yang Young Ho Kim Yung Hyun Choi Kyeong Sook Choi |
| Institution: | a Department of Immunology, School of Medicine, Keimyung University, 2800 Dalgubeoldaero, Dalseo-Gu, Daegu, 704-701, South Korea b Department of Anatomy, College of Medicine, Yeungnam University, 317-1 Daemyoung-Dong Nam-Gu, Daegu, South Korea c Department of Molecular Biology, College of Natural Science, Pusan National University, South Korea d Department of Molecular Biology and Immunology, College of Medicine, Kosin University, Busan, South Korea e Department of Pharmacology, School of Medicine, Kyungpook National University, Daegu, South Korea f Department of Biochemistry, College of Oriental Medicine, Dong-Eui University, Busan, South Korea g Institute for Medical Sciences, Ajou University School of Medicine, 5 Woncheon-Dong, Paldal-Gu, Suwon 442-749, South Korea |
| Abstract: | |
| Keywords: | Compound C TRAIL Mcl-1 c-FLIPL Apoptosis Reactive oxygen species |
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