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Vav1 and PU.1 are recruited to the CD11b promoter in APL-derived promyelocytes: Role of Vav1 in modulating PU.1-containing complexes during ATRA-induced differentiation |
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| Authors: | Federica Brugnoli Nadine Varin-Blank Roberta Piva Silvia Grassilli Silvano Capitani Valeria Bertagnolo |
| Institution: | a Signal Transduction Unit-Laboratory of Cell Biology, Section of Human Anatomy, Department of Morphology and Embryology, University of Ferrara, 44100 Ferrara, Italy b Department of Biochemistry and Molecular Biology, Molecular Biology Section, University of Ferrara, 44100 Ferrara, Italy c Inserm U978, Bobigny, France d Université Paris 13, Bobigny, France e Cell Signalling Unit, Department of Biomorphology, University “G. d'Annunzio” of Chieti-Pescara, 66013 Chieti, Italy f Center for Ageing Sciences (Ce.S.I.), Università “G.d'Annunzio” Foundation, Chieti, Italy g MIUR ICSI (Interdisciplinary Center for the Study of Inflammation), University of Ferrara, 44100 Ferrara, Italy |
| Abstract: | |
| Keywords: | APL acute promyelocytic leukemia ATRA all-trans retinoic acid PU 1 Purine-Rich box 1 GEF guanosine exchange factor PE phycoerythrin ChIP chromatin immunoprecipitation siRNA small interfering RNA EMSA electrophoretic mobility shift assays |
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