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Control of fibroblast fibronectin expression and alternative splicing via the PI3K/Akt/mTOR pathway
Authors:Eric S White  Rommel L Sagana  Mei Yan  Christopher A Bloomheart  Carol A Wilke  Jeffrey D Ritzenthaler  Andrés F Muro
Institution:
  • a Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
  • b Department of Medicine, University of Louisville School of Medicine, Louisville, KY, USA
  • c International Centre for Genetic Engineering and Biotechnology, Trieste, Italy
  • Abstract:
    Keywords:FN  fibronectin  EDA  extra type III domain &lsquo  A&rsquo    PI3K  phosphatidylinositol-3&rsquo  -kinase  PKB/Akt  protein kinase B/AKT  PTEN  phosphatase and tensin homologue on chromosome 10  mTOR  mammalian target of rapamycin  PIP3  phosphatidylinositol-3  4  5-trisphosphate  PH  pleckstrin homology  mEF  murine embryonic fibroblast  SR protein  splicing regulatory protein
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