Antimutagenic effect of chemosignals from isolated female house mouse on male germ cells (Mus musculus L.) |
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Authors: | E V Daev Yu A Bezruchko A V Dukelskaya |
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Institution: | 1. Department of Genetics and Biotechnology, Saint-Petersburg State University, Saint-Petersburg, 199034, Russia
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Abstract: | The influence of chemosignals from isolated mature females of the CBA strain on level of spontaneous and radiation-induced meiotic disturbances in spermatocytes I of males of the same strain was studied. Using an ana-telophase method, 24-hour exposure of males to soiled bedding containing isolated females’ chemosignals was shown to lead to a significantly lower frequency of chromosomal aberrations and other meiotic disturbances in spermatocytes I as compared to males kept on clean bedding. The same effect of female chemosignals was found in the germ cells of irradiated males (4 Gr). The mechanisms and importance of the revealed antimutagenic effect of mouse female chemosignals on the male reproductive cells in the reproduction process are discussed. |
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