胚胎期光照和皮质酮处理对日龄小鸡记忆的作用

该实验对胚胎发育后期的鸡胚进行光孵化，暗孵化以及药物注射处理后，采用一次性味觉被动回避行为模式观察它们对出生后小鸡记忆保持的影响并对其作用机制进行了初步探讨，结果表明胚胎期光照可增强小鸡记忆的保持，使用糖皮质激素受体拮抗剂可阻断光照对小鸡记忆的增强作用，对暗孵化鸡胚注射皮质酮可以促进出生后小鸡记忆的保持，因此皮质酮可能能与光照对小鸡记忆的增强过程，蛋白合成抑制剂在一定程度上阻断皮质醇对小鸡记忆的增

EFFECT OF PRENATAL LIGHT AND CORTICOSTERONE EXPOSURE ON MEMORY RETENTION OF DAY-OLD-CHICK

Light hatching, dark hatching and drugs were administrated to the 20-day-old embryos (E20). One-trial passive avoidance task has been used in this experiment to detect the effects of different treatments on memory retention of chicks and also the mechanism involved. Light exposure or corticosterone administration improved the memory retention of the chicks; the antagonist of glucocorticoid receptor RU-486 significantly retarded the memory retention of light-hatched chicks. Therefore, glucocorticoid and its receptor might be involved in the process of light exposure. The protein inhibitor anisomycin partly inhibited the effect of corticosterone. The data implicated that some mechanisms including synthesis of protein might be involved in this effect.